Bio-MESO

Brand Introduction

Metabolism Renewal, Youthful Vitality
Bio-MESO is a professional skincare brand under Bloomage Biotech, dedicated to cell metabolism and regulation. Bio-MESO provides cells with the energy they need to survive. Metabolic imbalance contributes to dullness, excess sebum, and premature aging.
Based on the national-level research strength of Bloomage Biotech, Bio-MESO has independently developed a "Metabolomics x Synthetic Biology x Intelligent Fermentation" research system to precisely regulate cellular metabolism and restore metabolic homeostasis. The brand's proprietary "Cell-level Metabolic Active Ingredient Library" provides precise metabolic energy for the skin, meeting multi-dimensional balanced metabolic needs, and scientifically defining skin rejuvenation.

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Metabolomics x Synthetic Biology x Intelligent Fermentation

Relying on the world's largest synthetic biology Pilot-scale Transformation Platform, with over 900 R&D personnel and 587 authorized patents under the group's name, Bloomage Biotech has entered the 5.0 era of biological manufacturing. The brand's unique "Metabolomics x Synthetic Biology x Intelligent Fermentation" technology, through the study of the metabolic pathways of bacterial strains and gene editing, aims to amplify or inhibit specific metabolic pathways of active ingredients, and in combination with intelligent fermentation and purification processes, produces "cell metabolic nutrient solutions" with specific types and proportions, achieving zero-impurity active ingredients and measurable efficacy, and achieving systemic regulation of cellular metabolic homeostasis.

Root cause for resolving skin metabolic imbalance
Return to skin that is pure, transparent, and bright

By regulating cellular metabolism through multiple network targets, this solution addresses the problems caused by skin metabolic imbalance at the root level and in a long-term manner. The CF-37 strain, a fifth-generation bio-manufactured strain, produces a "cellular metabolic nutrient solution" through synthetic fermentation. This solution provides the necessary nutrients for healthy metabolism to the cells, nurturing healthy and energetic skin cells, returning the skin to a state of purity, softness, radiance, and elasticity, and restoring skin health.

Many skin problems stem from the imbalance in the metabolism of skin cells.

Cells function as biochemical factories, converting ingested nutrients-including carbohydrates, lipids, and proteins-into energy and the building materials needed by the cells, while also eliminating metabolic waste to maintain life activities. Many skin problems arise from the imbalance in lipid, protein, sugar, and mitochondrial energy metabolism. Disordered lipid metabolism disrupts the skin's water-oil balance, compromising barrier function; impaired protein metabolism compromises skin structure; and dysregulated glucose metabolism accelerates aging, thereby causing various skin concerns.

By examining skin concerns at the cellular level, we uncover the underlying mechanisms

Through Bloomage Biotech's original metabolomics analysis technology, we systematically analyze the types and content changes of metabolites in skin cells, comprehensively map the metabolic networks of skin cells, identify over 40 key metabolic targets including DHT, PPARgamma, NF-kappaB, SREBP, IL-1beta, IL-6, COX-2, ROS, and mTOR, and use the active ingredient group synthesized by synthetic biology to achieve systemic regulation of the cell metabolic network, restoring cellular metabolic balance from the root cause.

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